Parkinson’sdisease相关论文
Decreased glial cell-derived neurotrophic factor and increased pro-inflammatory cytokines in the col
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Lesions of the globus pallidus externa(GPe)produce a profound sleep loss(~45%)in rats,suggesting that GPe neurons promot......
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The protective effect of NMDA receptor inhibitors on nigral iron accumulation in 6-OHDA-induced Park
Parkinsons disease(PD)is a neurodegenerative disease,which is mainly occurred in elderly person....
Protection effect of piperine and piperlonguminine from Piper longum L.alkaloids against rotenone-in
Objective Parkinson disease(PD)is a chronic progressive disease which could involve multiple systems at its early stage ......
Alteration of dopamine related oxidase in stomach and duodenum of 6-hydroxydopamine-induced Parkinso
Parkinsons disease(PD)is characterized by degeneration of dopaminergic neurons in the substantia nigra.Besides,the chang......
Nrf2-ARE signals mediated the anti-oxidative action of electro-acupuncture in an MPTP mouse model of
Oxidative stress and neuroinflammation are early events associated with dopaminergic neuronal degeneration in Parkinsons......
Neuroprotection of CDNF on dopaminergic neurons after proteasome inhibition via modulating Proteasom
Intracellular abnormal protein accumulations can be an important factor in the degeneration of dopaminergic neurons....
Regulatory mechanism of glutamate transporters expression by ubiquitin ligase E3 Nedd4-2 in Parkinso
Objective To study the molecular mechanism of abnormal glutamate transporter expression and function in Parkinsons disea......
Parkinsons disease(PD)is a neurodegenerative disease characterized by a movement disorder,including tremor,rigidity,brad......
Objective Lots of studies showed high frequency electro-acupuncture(EA)stimulation alleviated motor symptoms of parkinso......
Triptolide is a monomeric compound isolated from a traditional Chinese herb,tripterygium wilfordii Hook.f.(TWHF)....
The inflammasomes,which mediate the activation of caspase-1 and maturation of IL-1β and IL-18,has been unambiguously ve......
Non-motor symptoms are of vital importance in Parkinsons disease(PD)in recent years,among which cardiovascular dysfuncti......
Subcutaneous rotenone exposure causes selective dopaminergic degeneration and behavioral alterations
The systemic rotenone model of PD accurately replicates many aspects of the pathology of human PD.However,the major limi......
Aging is associated with an increased risk for Parkinsons disease(PD)and dementia with Lewy bodies(DLB),in which alpha-s......
The Influence of Substantia Nigra Neurons and Akt through Acupuncture of Chorea-tremble Controlled A
Objective To study the protective effect of acupuncture of Chorea-tremble controlled area combined with madopar on the d......
Progressive accumulation of α-synuclein is a key step to pathological development of Parkinsons disease and dementia wi......
Anti-Parkinsonian effects of Polygonum multiflorum Thunb.on transgenic and pharmacological Caenorhab
Objective: Polygonum multiflorum Thunb.is more commonly used in Chinese herbs/constituents (e.g.Kang Zhen Zhi Jing No.1 ......
Serum and cerebrospinal fluid levels of transthyretin in Lewy body disorders with and without dement
Parkinson’s disease (PD) without (non-demented,PDND) and with dementia (PDD),and dementia with Lewy bodies (DLB) are su......
Quantified assessment of deep brain stimulation on Parkinson’s patients with task fNIRS measurements
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Parkinsonism-hyperpyrexia syndrome after withdrawal of antiparkinsonian drugs and deep brain stimula
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Quantified assessment of deep brain stimulation on Parkinson’s patients with task fNIRS measurements
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Rapid Eye Movement Sleep Behavior Disorder Symptoms Correlate with Domains of Cognitive Impairment i
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Relationships between Rapid Eye Movement Sleep Behavior Disorder and Neurodegenerative Diseases: Cli
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Target Selection Recommendations Based on Impact of Deep Brain Stimulation Surgeries on Nonmotor Sym
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Dopamine Agonists Exert Nurr1-inducing Effect in Peripheral Blood Mononuclear Cells of Patients with
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Tonic Electromyogram Density in Multiple System Atrophy with Predominant Parkinsonism and Parkinson’
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Altered regional homogeneity of prefrontal cortex in Parkinson’s disease with mild cognitive impairm
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目的观察节律性听觉刺激(RAS)辅助左旋多巴(L-Dopa)片治疗老年帕金森病(PD)的效果。方法抽取2019年1月至2020年12月郑州市第二人民......
Quantified assessment of deep brain stimulation on Parkinson’s patients with task fNIRS measurements
Background::Deep brain stimulation (DBS) has proved effective for Parkinson’s disease (PD), but the identification of s......
Effect of stromal cell-derived factor-1/CXCR4 axis in neural stem cell transplantation for Parkinson
Previous studies have shown that neural stem cell transplantation has the potential to treat Parkinson’s disease, but i......
目的 比较1-甲基-4-苯基-1,2,3,6-四氢吡啶(MPTP)所致的急性、亚急性和慢性帕金森病(PD)模型小鼠空间参考记忆和脑内多巴胺(DA)水......
目的 探讨钙调激酶Ⅱ抑制剂KN-93对帕金森病运动并发症大鼠行为学及GluR1831位丝氨酸磷酸化的影响.方法 将6-羟基多巴立体定向注射......
目的 探讨帕金森病(PD)非运动症状的发生、不同运动症状分级(H-Y)时的分布及其影响因素.方法 用统一PD评分量表Ⅲ和Ⅴ(UPDRS-Ⅲ、U......
目的 利用大鼠脑室内注射低剂量脂多糖(lipopolysaccharide,LPS)(10μg)诱导全脑炎症,长时间观察大鼠行为学、黑质部位小胶质细胞......
目的观察6-羟基多巴胺(6-OHDA)诱导的帕金森病(PD)大鼠纹状体透析液中,5-羟吲哚乙酸(5-HIAA)和褪黑素的动态变化及其与多巴胺的关系......